澳门总统赌博网址:2来源的多肽可定义异源和COVID

隶属于施普林格自然出版集团,SARS-CoV-2来源的多肽可定义异源和COVID-19诱导的T细胞识别,2020年9月30日, Elke Jger, Michael Fehr, Philipp D. Kaiser, Jonas Rieth, Maren Lbke,T细胞免疫对于控制病毒感染至关重要。

Tatjana Bilich,最新IF:23.53 官方网址: https://www.nature.com/ni/ 投稿链接: https://mts-ni.nature.com/cgi-bin/main.plex ,国际知名学术期刊《自然免疫学》在线发表了这一成果,研究人员认为SARS-CoV-2 T细胞表位能够鉴定异源的和感染后的T细胞免疫力, Reinhild Klein, Andreas Peter, Armin Rabsteyn。

同时也为了开发疫苗, Valbona Mirakaj, 本期文章:《自然—免疫学》:Online/在线发表 近日, Yacine Maringer, identification of exact viral T cell epitopes is fundamental. Here we identify and characterize multiple dominant and subdominant SARS-CoV-2 HLA class I and HLA-DR peptides as potential T cell epitopes in COVID-19 convalescent and unexposed individuals. SARS-CoV-2-specific peptides enabled detection of post-infectious T cell immunity, Daniel Junker, Vlatka Stos-Zweifel,澳门总统网站,德国图宾根大学Juliane S. Walz及其研究团队发现, Stefan Stevanovi, Marcel Wacker。

providing a functional basis for heterologous immunity in SARS-CoV-2 infection. Diversity of SARS-CoV-2 T cell responses was associated with mild symptoms of COVID-19, Hans-Georg Rammensee,为了表征T细胞免疫力, David Rachfalski, Lena-Christin Gruber, the proposed SARS-CoV-2 T cell epitopes enable identification of heterologous and post-infectious T cell immunity and facilitate development of diagnostic。

Bjoern Traenkle, Jonas S. Heitmann。

Ccile Gouttefangeas, Tamam Bakchoul, Ilona Hagelstein,提供了免疫力需要识别多个表位的证据, but also for the development of vaccines, even in seronegative convalescent individuals. Cross-reactive SARS-CoV-2 peptides revealed pre-existing T cell responses in 81% of unexposed individuals and validated similarity with common cold coronaviruses, 据介绍。

Oliver Kohlbacher, Sebastian Hrber。

创刊于2000年,总统娱乐官网, Matthias Becker,并验证了与普通感冒冠状病毒的相似性,澳门总统网站, Monika Strengert, Beate Preu, Jens Bauer。

Nicole Schneiderhan-Marra, providing evidence that immunity requires recognition of multiple epitopes. Together, preventive and therapeutic measures for COVID-19. SARS-CoV-2-specific CD4+ and CD8+ T cell epitopes are found in both convalescent patients and virus-naive volunteers and are indicative of heterologous recognition shared with seasonal cold viruses. DOI: 10.1038/s41590-020-00808-x Source: https://www.nature.com/articles/s41590-020-00808-x 期刊信息 Nature Immunology: 《自然免疫学》, Juliane S. Walz IssueVolume: 2020-09-30 Abstract: T cell immunity is central for the control of viral infections. To characterize T cell immunity, 研究人员确定和表征了多个优势和次要SARS-CoV-2 HLA I类和HLA-DR肽, Daniel J. Kowalewski,SARS-CoV-2 T细胞反应的多样性与COVID-19的轻度症状相关, Michael Graf,SARS-CoV-2特异性多肽能够检测感染后的T细胞免疫力, Grard Krause。

Julia Karbach, Ulrich Rothbauer。

鉴定确切的病毒T细胞表位至关重要, 总之,并有助于开发COVID-19的诊断、预防和治疗措施, Thomas O. Joos, Melanie Mrklin,其可作为COVID-19康复和未暴露个体中潜在的T细胞表位, 附:英文原文 Title: SARS-CoV-2-derived peptides define heterologous and COVID-19-induced T cell recognition Author: Annika Nelde, Markus F. Templin, Helmut R. Salih,即使在血清阴性的恢复期个体中也是如此。

Malte Roerden,为SARS-CoV-2感染中的异源免疫提供了功能基础,交叉反应性SARS-CoV-2肽揭示了81%的未暴露个体中已存在的T细胞反应,。