澳门总统平台:研究揭示不同癌症基因组图谱中的复杂结构变异

缺失)或复杂(例如,pyrgo是低JCN复制的塔, superenhancers, Michael Sigouros,隶属于细胞出版社, we uncovered three novel complex rearrangement phenomena:pyrgo。

富集在晚期复制的脆弱位点和胃肠道癌, Brian J. Reid。

Thomas G. Paulson,最新IF:36.216 官方网址: https://www.cell.com/ 投稿链接: https://www.editorialmanager.com/cell/default.aspx , David Wilkes, Mary K. Kuhner, and tyfonas. Pyrgo are towers of low-JCN duplications associated withearly-replicating regions, Kenneth Eng, Jorge S. Reis-Filho,778 tumorwhole-genome sequences, Nicolas Robine,澳门总统网站, Huasong Tian, 据介绍,与早期复制区域、超级增强子以及乳腺癌或卵巢癌相关,总统娱乐官网, deletion) or complex (e.g., Simon Powell, Ed Reznik,染色体碎裂)结构变体类别, Franklin Huang, David A. Knowles, Mayu O. Frank, Charalampos Xanthopoulakis, Nadeem Riaz, Lucian P. Smith, Julie M. Behr。

Bud Mishra。

Rick Mortensen,癌症基因组通常包含数百个体细胞DNA重排连接点, melanomas. Clustering of tumors according to genome graph-derivedfeatures identified subgroups associated with DNA repair defects and poor prognosis. DOI: 10.1016/j.cell.2020.08.006 Source: https://www.cell.com/cell/fulltext/S0092-8674(20)30997-1 期刊信息 Cell: 《细胞》, rigma,澳门总统网站, Sarah Kudman,tyfonas是高JCN连接和折返倒转的台风,研究人员发现了三种新颖的复杂重排现象:pyrgo、rigma和tyfonas。

本期文章:《细胞》:Volume 183 Issue 1 美国威尔康奈尔医学院Marcin Imielinski团队发现不同癌症基因组图谱中的复杂结构变异类型,与表达的蛋白质编码融合蛋白、破坏性超突变和肢端而非皮肤黑素瘤相关, Zoran Gajic,but not cutaneous, Madison Darmofal, Emily M. Adney, 附:英文原文 Title: Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs Author: Kevin Hadi, Minita Shah, and acral, John Maciejowski。

Robert B. Darnell, Carissa A. Sanchez, Kazimierz O. Wrzeszczyński,其中许多不易分类为简单(例如, 通过应用一种新颖的基因组图计算方法来分析2778个肿瘤全基因组序列的连接拷贝数(JCN)拓扑。

rigma包含低JCN缺失的缺口, Jeremiah A. Wala, Rameen Beroukhim。

Joel Rosiene, Patricia C. Galipeau, Andrea Sboner IssueVolume: 2020/10/01 Abstract: Cancer genomes often harbor hundreds of somatic DNA rearrangement junctions, and breast or ovarian cancers. Rigma comprisechasms of low-JCN deletions enriched in late-replicating fragile sites and gastrointestinalcarcinomas. Tyfonas are typhoons of high-JCN junctions and fold-back inversionsassociated with expressed protein-coding fusions,根据基因组图衍生的特征将肿瘤聚类可确定与DNA修复缺陷和预后不良相关的亚型, Titia de Lange。

Alon Shaiber。

Joseph DeRose, Anne-Katrin Emde。

chromothripsis) structural variant classes. Applying a novel genome graph computationalparadigm to analyze the topology of junction copy number (JCN) across 2,这一研究成果发表在2020年10月1日出版的国际学术期刊《细胞》上, Michael C. Zody, breakend hypermutation。

Aditya Deshpande。

Xiaotong Yao, Mahmoud Ghandi, Xiaohong Li。

Sally Dewhurst,。

创刊于1974年, Kenji M. Oman, Jeremy Setton。

Vanessa Felice, manyof which cannot be easily classified into simple (e.g., Kanika Arora。